陳維,博士,教授,博士生導師,就職于伟德官网下载客户端制藥工程。2018年入選“江蘇省特聘教授”。2010年獲蘇州大學碩士學位,并榮獲“江蘇省優秀碩士研究生學位論文”;2013年獲荷蘭University of Twente博士學位(導師:Jan Feijen教授和鐘志遠教授)。2013-2017年在德國Freie Universität Berlin博士後研究(合作導師:Rainer Haag教授);2015年開始主持德國洪堡博士後基金項目。目前課題組研究興趣主要涉及“智能型可降解微納藥物”、“微流控技術制備凝膠藥物”、“藥物高效分離與制粒工藝”等,已在化學、藥學、生物材料學等領域的國際知名學術期刊如:Angew. Chem.、J. Control. Release、Biomaterials、Small、Macromolecules等發表論文40餘篇,論文引用2200餘次(2篇ESI高被引)。目前以第一發明人身份已獲得授權的歐洲專利、美國專利和中國專利各1項,正主持國家自然科學基金項目2項,江蘇省人才項目1項,江蘇省自然科學基金項目1項,南京市留學人員科技創新項目1項。
Email:w.chen@cpu.edu.cn。
代表性文章(注*為通訊作者)
1. Haishi Qiao, Xingmei Chen, Qiming Wang, Junmei Zhang, Dechun Huang, Enping Chen, Hongliang Qian, Yinan Zhong*, Qi Tang*, and Wei Chen*, Tumor Localization of Oncolytic Adenovirus Assisted by pH-Degradable Microgels with JQ1-Meidated Boosting Replication and PD-L1 Suppression for Enhanced Cancer Therapy, Biomater. Sci.2020, 8, 2472-2480.
2. Xingmei Chen, Hongliang Qian, Haishi Qiao, Bin Dong, Enping Chen, Dechun Huang*, Ting Wang, and Wei Chen*, Tumor-Adhesive and pH-Degradable Microgels by Microfluidics and Photo-Cross-Linking for Efficient Antiangiogenesis and Enhanced Cancer Chemotherapy, Biomacromolecules2020, 21, 3, 1285-1294.
3. L.L. Gao, B. Dong, Y. Chen, H.S. Qiao, Z.H. Liu, E.P. Chen, Y.Q. Dong, C.J. Cao*, D.C. Huang, and Wei Chen*, Functional Biodegradable Nitric Oxide Donor-Containing Polycarbonate-Based Micelles for Reduction-Triggered Drug Release and Overcoming Multidrug Resistance, ACS Macro Lett. 2019, 8, 1552-1558.
4. Q. Zhao, S.Y. Zhang, F.C. Wu, D.Y. Li, X.J. Zhang*, W. Chen*, B.S. Xing*, Rational Design of Nanogels for Overcoming The Biological Barriers in Various Administration Routes, Angew. Chem. Int. Ed. 2019, https://doi.org/10.1002/ange.201911048.
5. H.S. Qiao, X.M. Chen, E.P. Chen, J.M. Zhang, D.C. Huang*, D.Q. Yang, Y.C. Ding, H.L. Qian, J. Feijen, and W. Chen*, Folated pH-Degradable Nanogels for Simultaneous Delivery of Docetaxel and IDO1-Inhibitor in Enhancing Cancer Chemo-Immunotherapy, Biomater. Sci.2019, 7, 2749-2758.
6. H.S. Qiao, J. Jia, H.W. Shen, S.B. Zhao, E.P. Chen, W. Chen*, B. Di*, C. Hu*, Capping Silica Nanoparticles with Tryptophan-Mediated Cucurbit[8]Uril Complex for Targeted Intracellular Drug Delivery Triggered by Tumor-Overexpressed IDO1 Enzyme, Adv. Healthcare Mater.2019, 8, 1900174.
7. Z. Tu, H. Qiao, Y. Yan, G. Guday, W. Chen*, M. Adeli*, and R. Haag*, Directed Graphene-Based Nanoplatforms for Hyperthermia: Overcoming Multiple Drug Resistance, Angew. Chem.2018, 130, 11368 –11372 (Angew. Chem. Int. Ed. 2018, 57, 11198 –11202).
8. Y. Hou, W.Y. Xie, K. Achazi, J.L. Cuellar-Camacho, M.F. Melzig, W. Chen*, and R. Haag*, Injectable Degradable PVA Microgels Prepared by Microfluidic Technology for Controlled Osteogenic Differentiation of Mesenchymal Stem Cells, Acta Biomater.2018, 77, 28-37.
9. W. Chen, P. Zhong, F.H. Meng*, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Redox and pH-Responsive Degradable Micelles for Dually Activated Intracellular Anticancer Drug Release, J. Control. Release2013, 169, 171-179.(ESI高被引)
10. W. Chen, F.H. Meng*, R. Cheng, Z.Y. Zhong*,pH-Sensitive Degradable Polymersomes for Triggered Release of Anticancer Drugs: a Comparative Study with Micelles, J. Control. Release2010, 142, 40-46.(ESI高被引)