胡馳,副研究員,郵箱chihu@cpu.edu.cn。本科就讀于同濟大學材料科學與工程學院,碩士、博士畢業于英國劍橋大學化學系。于2016年加入伟德官网下载客户端,開發了一些列針藥物-靶标相互作用、精神活性物質痕量檢測的新型分析方法。研究内容獲得國家自然科學基金、江蘇省自然科學基金資助,研究内容發表于Anal. Chem.等分析化學領域頂級期刊。

 

 研究方向:

      1、 毒品吸食人員快速篩查方法;

      2、 環境毒品快速檢測試劑盒;

      3、 疾病相關靶點診斷方法。

 

代表性科研成果:

[1] Sibo Zhao, Huilin Wen, Yangteng Ou, Minhui Li, Lancheng Wang, Huimin Zhou, Bin Di, Ziyi Yu*, and Chi Hu*, A new design for living cell-based biosensors: microgels with a selectively permeable shell that can harbor bacterial species. Sensors and Actuators B: Chemical, 2021. 334: p. 129648. 


[2] Li-li Xu, Cui-cui Li, Lu-yan An, Zhen Dai, Xiao-yi Chen, Qi-dong You*, Chi Hu*, and Bin Di*, Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRASG12C. European Journal of Medicinal Chemistry, 2020. 185: p. 111844.


[3] Cheng, S., Shen, H., Zhao, S., Zhang, Y., Xu, H., Wang, L., Di, B.*, Xu, L.*, and Hu, C.*, Orally administrated mesoporous silica capped with cucurbit[8]uril complex to combat colitis and improve intestinal homeostasis by targeting gut microbiota. Nanoscale, 2020. 12: p. 15348-15363.


[4] Jia, J., Wen, H., Zhao, S., Wang, L., Qiao, H., Shen, H., Yu, Z., Di, B.*, Xu, L.*, and Hu, C.*, Displacement induced off-on fluorescent biosensor targeting IDO1 activity in live cells. Analytical Chemistry, 2019. 91(23): p. 14943-14950.


[5] Qiao, H., Jia, J., Shen, H., Zhao, S., Chen, E., Chen, W.*, Di, B.*, and Hu, C.*, Capping silica nanoparticles with tryptophan-mediated cucurbit[8]uril complex for targeted intracellular drug delivery triggered by tumor-overexpressed IDO1 enzyme. Advanced Healthcare Materials, 2019. 8(13): p. 1900174.


[6] Qiao, H., Jia, J., Chen, W., Di, B., Scherman, O. A., and Hu, C.*, Magnetic regulation of thermo-chemotherapy from a cucurbit[7]uril-crosslinked hybrid hydrogel. Advanced Healthcare Materials, 2019. 8(2): p. 1801458.


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