王鵬,博士,副教授,博士生導師。伟德官网下载客户端伟德官网下载客户端生物醫學工程教研室。主要從事小分子熒光探針在腫瘤早期診斷中的應用、靶向抗腫瘤藥物分子的設計活性研究、基于有機小分子熒光探針的智控載藥系統等方面的研究。主持國家自然科學基金、江蘇省自然科學基金、中央高校基本科研項目以及校級項目多項。入選江蘇省青藍工程優秀青年骨幹教師(2018)、江蘇省雙創計劃“科技副總”(2018)等計劃。近5年以第一作者或通訊作者在Chemical Science、Small、BiomaterialsBiosensors and BioelectronicsACS Applied Materials & Interfaces、Sensors and Actuators B: ChemicalAnalytica Chimica ActaEuropean Journal of Medicinal ChemistryMolecular Pharmaceutics、Nanomedicine等學術期刊發表SCI學術論文四十餘篇;申請中國發明專利6項,授權4項;參與研發的抗腫瘤1.1類新藥于20204月進入II期臨床試驗。


主要學習及工作經曆:
2014.7—至今伟德官网下载客户端伟德官网下载客户端

2018.102019.10 美國哈佛醫學院/麻省總醫院Martinos Center 訪問學者
2011.32014.6 東南大學生物醫學工程專業 博士
2005.92008.6 伟德官网下载客户端藥學院藥物化學專業 碩士
2001.92005.6 山東大學藥學院藥學專業本科


研究興趣:
小分子熒光探針在腫瘤早期診斷及診療中的應用
靶向抗腫瘤藥物分子的設計活性研究
基于有機小分子熒光探針的智控載藥系統


代表性論文

1. Jing Yang, Biyue Zhu, Wei Yin, Zhihao Han, Chao Zheng, Peng Wang*, Chongzhao Ran*. Differentiating Aß40 and Aß42 in amyloid plaques with a small molecule fluorescence probe. Chemical Science, 2020.

2. Han Wang, Zhaohui Wang, Yuanbiao Tu, Yongkuan Li, Tian Xu, Man Yang, Peng Wang, Yueqing Gu. Homotypic targeting upconversion nano-reactor for cascade cancer starvation and deep-tissue phototherapy. Biomaterials, 235 (2020) 119765

3. Han Wang, Zhaohui Wang, Yongkuan Li, Tian Xu, Qi Zhang, Man Yang, Peng Wang,* Yueqing Gu*.A Novel Theranostic Nanoprobe for In Vivo SingletOxygen Detection and Real-Time Dose–Effect Relationship Monitoring in Photodynamic Therapy, Small, 2019, 1902185.

4. Wang Peng*Wang QianqianHuang JinxinLi NanGu Yueqing *A dual-site fluorescent probe for direct and highly selective detection of cysteine and its application in living cells,Biosensors and Bioelectronics,2017,92583~588.

5. Han Wang, Yongkuan Li, Man Yang, Peng Wang*, and Yueqing Gu*, FRET-Based Upconversion Nanoprobe Sensitized by Nd3+ for theRatiometric Detection of Hydrogen Peroxide in Vivo, ACS Appl. Mater. Interfaces 2019, 11, 7441−7449.

6. Lili Xia, Fang Hu, Jinxin Huang, Nan Li, Yueqing Gu*, Peng Wang*, A fluorescent turn-on probe for nitroreductase imaging in living cellsand tissues under hypoxia conditions, Sensors and Actuators B, 2018, 268: 70–76.

7. Yuxiang Ma, Ying Zhao, Lili Xia, Jinxin Huang, Yueqing Gu, Peng Wang*, A novel one- and two-photon fluorescent probe induced by light for selective imaging of Cys in living cells and tissues, Analytica Chimica Acta, 2018, 1035: 161-167.

8. Huang JinxinLi NanWang QianqianGu Yueqing*Wang Peng*A lysosome-targetable and two-photon fluorescent probe for imaging endogenous β-galactosidase in living ovarian cancer cellsSensors and Actuators B: Chemical2017246833~839.

9. Wang Peng*Huang JinxinWang KeGu Yueqing*New Palbociclib analogues modified at the terminal piperazine ring and their anticancer activitiesEuropean Journal of Medicinal Chemistry2016122546~556.

10. Wang Peng*Cai JinChen JunqingJi Min*Synthesis and anticancer activities of ceritinib analogs modified in the terminal piperidine ringEuropean Journal of Medicinal Chemistry2015931~8.


聯系方式:
wangpeng@cpu.edu.cn


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