李斯文,教授,博士研究生導師,國家優秀青年基金獲得者,伟德官网下载客户端興藥領軍學者。2020年江蘇省青藍工程優秀青年骨幹教師,國家自然科學基金通訊評審專家,中國生物醫學工程學會-生物光子學分會青年委員、江蘇省生物醫學工程學會副秘書長,江蘇省藥物研究與開發協會-醫療器械與藥學裝備專業委員會協會秘書、江蘇省診斷試劑學會委員、多個SCI收錄期刊審稿人。現任伟德官网下载客户端伟德官网下载客户端生物醫學工程與診斷藥學系支部書記。目前已主持縱向研究項目包括國家自然科學基金優秀青年項目、面上項目、青年項目、重大科研儀器研制項目(合作方負責人)以及江蘇省自然科學基金-優秀青年基金項目、青年基金項目(結題優秀)等;主持熒光體外診斷試劑開發橫向項目兩項;專利技術“抗 HPV 光調制納米微乳凝膠”等科技成果已在企業落地轉化;參與國家基礎研究計劃(973 計劃)及國家自然科學基金-重點項目等;獲教育部高等學校科學研究優秀成果獎自然科學獎二等獎等獎項。

近年來,以第一或通訊作者身份在 Science Advances (IF=14.136),ACS Nano (IF=15.881), Advanced Science (IF=16.806), Biomaterials (IF=12.479), Chemical Engineering Journal (IF=13.273), Cancer Research (IF=12.701), Applied Materials Today (IF=10.041) 等國際權威期刊中發表 SCI 論文 19 篇(10 篇 IF>10)。研究成果被Nature Reviews Drug Discovery, Nature Reviews Materials, Chemical Society Reviews, Advanced Drug Delivery Reviews 等權威期刊及國家科技部官網等媒體亮點報道。申請專利 20項,獲授權專利11 項。受邀在領域内國際學術會議做邀請報告 20 次以上。


教育經曆及工作經曆:

2023-07 至今,    伟德官网下载客户端,伟德官网下载客户端,教授

2018-07 2023-07, 伟德官网下载客户端, 伟德官网下载客户端, 副教授

2015-07 2018-06, 伟德官网下载客户端, 伟德官网下载客户端, 講師

2010-09 2015-06, 伟德官网下载客户端, 微生物與生化藥學, 博士

2006-09 2010-06, 伟德官网下载客户端, 生物工程, 學士


研究方向:

1、基于幹細胞囊泡的體内靶向治療策略研究

2、體外診斷試劑開發及應用研究

3、功能性大健康産品開發研究


近五年代表性論文:

(1) Yuewen Zhai; Xiaorong He; Ying Li; Ran Han; Yuying Ma; Peng Gao; Zhiyu Qian; Yueqing Gu; Siwen Li ; A splenic-targeted versatile antigen courier: iPSC wrapped in coalescent erythrocyte-liposome as tumor nanovaccine, Science Advances, 2021, 7(35): eabi6326. (IF=14.136)

(2) Tian Xu; Yuying Ma; Qinling Yuan; Huixin Hu; Xinkai Hu; Zhiyu Qian; Janiqua Kyiesha Rolle; Yueqing Gu; Siwen Li ; Enhanced Ferroptosis by Oxygen-boosted Phototherapy Based on 2-in-1 Nano platform of Ferrous Hemoglobin for Tumor Synergistic Therapy, ACS Nano, 2020, 14(3): 3414-3425. (IF=15.881)

(3) Yuying Ma; Jinnan Zhang; Yalan Rui; Janiqua Rolle; Tian Xu; Zhiyu Qian; Yueqing Gu; Siwen Li ; Depletion of glioma stem cells by synergistic inhibition of mTOR and c-Myc with a biological camouflaged cascade brain-targeting nanosystem, Biomaterials, 2021, 268: 120564. (IF=12.479)

(4) Yuying Ma; Yanqin Zhang; Ran Han; Ying Li; Yuewen Zhai; Zhiyu Qian; Yueqing Gu; Siwen Li; A cascade synergetic strategy induced by photothermal effect based on platelet exosome nanoparticles for tumor therapy., Biomaterials, 2022, 282: 121384. (IF=12.479)

(5) Ying Li; Chunjiao Wu; Yuewen Zhai; Ran Han; Ruoyu Gu; Yuying Ma; Peng Gao; Zhiyu Qian; Yueqing Gu; Siwen Li ; Palliating the escalated post-PDT tumor hypoxia with a dual cascade oxygenation nanocomplex, Applied Materials Today, 2022, 26: 101287. (IF=10.041)

(6) Yuewen Zhai; Yuying Ma; Bo Pang; Jinnan Zhang; Ying Li; Yalan Rui; Tian Xu; Yu Zhao; Zhiyu Qian; Yueqing Gu; Siwen Li ; A cascade targeting strategy based on modified bacterial vesicles for enhancing cancer immunotherapy, Journal of Nanobiotechnology, 2021, 19(1): 434.(IF=10.435)

(7) Ping Li; Mengqiu Gao; Zijian Hu; Tian Xu; Jieru Chen; Yuxuan Ma; Siwen Li; Yueqing Gu ; Synergistic ferroptosis and macrophage re-polarization using engineering exosome-mimic M1 nanovesicles for cancer metastasis suppression, Chemical Engineering Journal, 2021, 409: 128217. (IF=13.273)

(8) Zhaohui Wang; Siwen Li; Min Zhang; Yi Ma; Yuxi Liu; Weidong Gao; Jiaqi Zhang; Yueqing Gu; Laser-Triggered Small Interfering RNA Releasing Gold Nanoshells against Heat Shock Protein for Sensitized Photothermal Therapy, Advanced Science, 2016, 4(2): 1600327. (IF=16.806)

(9) Jie Cao; Sisi Cui; Siwen Li; Changli Du; Junmei Tian; Shunan Wan; Zhiyu Qian; Yueqing Gu; Wei R Chen; Guangji Wang ; Targeted cancer therapy with a 2-deoxyglucose-based adriamycin complex, Cancer Research, 2013, 73(4): 1362-1373(IF=12.701)

(10) Siwen Li; Yuxi Liu; Yalan Rui; Liping Tang; Samuel Achilefu; Yueqing Gu ; Dual target gene therapy to EML4-ALK NSCLC by a gold nanoshell-based system, Theranostics, 2018, 8(10): 2621-2633(IF=11.556)


聯系方式:lsw@cpu.edu.cn



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