李振,教授,博士生導師,伟德官网下载客户端“興藥領軍學者”
2024.02-今 伟德官网下载客户端,教授
2020.08-2024.01 美國Scripps研究所,博士後,師從餘金權(Jin-Quan Yu)教授
2016.09-2020.07 揚州大學,博士,師從段偉良教授
2013.09-2016.07 上海應用技術大學與上海有機化學研究所聯合培養, 碩士,師從段偉良教授
1. 藥物分子後期修飾:設計高效的化學合成新技術,以實現複雜藥物分子的精準修飾,進而優化其生物活性。
2. 藥物規模化制備:開發綠色且經濟的化學生産新技術,以高效應用于藥物合成,從而顯著降低生産成本。
1. Li, Z.#; Wang, Z.#; Chekshin, N.; Qian, S.; Qiao, J. X.; Cheng, P. T.; Yeung, K.-S.; Ewing, W. R.; Yu, J.-Q.* A tautomeric ligand enables directed C‒H hydroxylation with molecular oxygen. Science2021, 372, 1452.
2. Li, Z.#; Park, H. S.#; Qiao, J. X.; Yeung, K.-S.; Ewing, W. R.; Yu, J.-Q.* Ligand-enabled C−H hydroxylation with aqueous H2O2 at room temperature. J. Am. Chem. Soc. 2022, 144, 18109.
3. Li, Z.; Yu, J.-Q.* Ligand-enabled-C(sp3)−H hydroxylation of free amines with aqueous hydrogen peroxide. J. Am. Chem. Soc. 2023, 145, 25948.
4. Li, Z.; Lin, Z.-Q.; Yan, C.-G.; Duan, W.-L.* Pd-catalyzed asymmetric C−H bond activation for the synthesis of Pstereogenic dibenzophospholes. Organometallics 2019, 38, 3916.
5. Li, Z.; Duan, W.-L.* Palladium-catalyzed C−H alkenylation of arenes with alkynes: stereoselective synthesis of vinyl chlorides via a 1,4-chlorine migration. Angew. Chem. Int. Ed. 2018, 57, 16041.