袁振偉,博士,副教授,研究生導師,先後入選江蘇省“科技副總”計劃、安徽省“科技副總”計劃、“博士後創新人才支持計劃”,獲廈門市科技進步獎三等獎(3/3),并擔任江蘇省生物醫學工程學會生物醫學光子學分會青年委員、《伟德官网下载客户端學報》青年編委。圍繞腫瘤等重大疾病精準診療與放射治療中的的臨床問題,先後主持國家重點研發計劃課題、國家自然科學基金、江蘇省産學研合作項目、中央高校科研業務費重點項目、拉薩市重點科技計劃項目、伟德官网下载客户端-南京中硼聯康醫療科技有限公司聯合實驗室項目、伟德官网下载客户端-安徽中萊實業有限公司健康金寨聯合實驗室項目等,并以第一作者或者通訊作者在核化學、藥物化學、以及化學生物學等領域權威期刊等刊物發表SCI論文30餘篇,申請專利8項;并積極與醫院、企業開展産學研合作。近年來,指導學生先後獲得中國國際大學生創新大賽國賽金獎、全國大學生生命科學競賽國賽特等獎、全國生物醫學工程創新設計競賽國賽一等獎、江蘇省生物醫學工程創新競賽特等獎等獎項。
基于硼中子俘獲治療(BNCT)的靶向硼藥的設計合成及其成藥性研究
基于疾病診療導向的光學/超聲學分子開發
Jingxuan Guo, Jia Sun, Donghui Liu, Ji Liu, Lijuan Gui, Man Luo, Dexin Kong, Sainaiwaiergul Wusiman, Chang Yang, Ting Liu,* Zhenwei Yuan*, and Ruixi Li*, Developing a Two-Photon “AND” Logic Probe and Its Application in Alzheimer’s Disease Differentiation, Analytical Chemistry, 2023, 95, 16868−16876.
Jun Yan, Kaizhen Wang, Lijuan Gui, Xian Liu, Yingying Ji, Jingjing Lin, Man Luo, Hong Xu, Jingxuan Lv, Fang Tan,* Liangting Lin,* and Zhenwei Yuan*, Diagnosing Orthotopic Lung Tumor Using a NTR-Activatable Near Infrared Fluorescent Probe by Tracheal Inhalation, Analytical Chemistry, 2023, 95, 14402−14412.
Lijuan Gui, Jun Yan, Junyuan Zhao, Shiya Wang, Yingying Ji, Ji Liu, Jinsheng Wu, Kang Yuan, Heng Liu,* Dawei Deng* and Zhenwei Yuan*, Hypochlorite activatable ratiometric fluorescent probe based on endoplasmic reticulum stress for imaging of atherosclerosis, Biosensors and Bioelectronics, 2023, 240, 115660.
Ruixi Li, Jingxuan Guo, Yishan Duan, Xian Liud, Lijuan Guib, Yue Xu, Xiangkai Kong, Yongjun Li, Haiyan Chen,* Zhenwei Yuan*, Monitoring inflammation-cancer progression by cell viscosity, polarity and leucine aminopeptidase using multicolor fluorescent probe, Chemical Engineering Journal, 2022, 435, 135043.
Yue Xu, Hua Li, Shufen Xu, Xian Liu, Jingjing Lin, Haiyan Chen,* and Zhenwei Yuan*, Light-Triggered Fluorescence Self-Reporting Nitric Oxide Release from Coumarin Analogues for Accelerating Wound Healing and Synergistic Antimicrobial Applications, Journal of Medicinal Chemistry, 2022, 65, 424−435.