主要從事有機小分子化合物在疾病診斷與治療中的應用。入選江蘇省“333工程”第三層次、江蘇省“青藍工程”優秀青年骨幹教師、江蘇省雙創計劃“科技副總”等計劃；《藥學研究》青年編委；國家自然科學基金、荷蘭研究理事會（Dutch Research Council, NWO）項目評審專家。

近5年以通訊作者在Coordin Chem Rev、Chem Eng J、Analytical Chemistry、Small、Biomaterials、Chem Sci、Biosens Bioelectron、AHM、ACS App Mater Inter等期刊發表SCI學術論文五十餘篇；申請專利10餘項，授權6項。參與研發的抗腫瘤1類新藥安奈克替尼（TQ-B3101/Unecritinib）成功上市。

指導本科生獲得挑戰杯全國競賽江蘇省二等獎、全國大學生生命科學創新創業大賽二等獎；指導研究生獲得江蘇省優秀學位論文（2人）、國家獎學金（9人次）、江蘇省優秀畢業生（2人）、校長獎學金（1人）等。

1. 有機小分子診療探針；

2. 抗腫瘤新藥發現研究；

3. 原料藥和生物化工産品工藝開發。

主持國家自然科學基金面上項目和青年項目、江蘇省自然科學基金等項目。

1. Self-assembly strategies of organic small-molecule photosensitizers for photodynamic therapy. Coordination Chemistry Reviews, 2024, 510, 215863

2. Visualization of the Ferroptosis in Atherosclerotic Plaques with Nanoprobe Engineered by Macrophage Cell Membranes. Anal. Chem. 2024, 96, 281-291

3. A sulfatase-activatable AIEgen nanoprobe for inhalation imaging-guided surgical excision of lung cancer. Chemical Engineering Journal, 2022, 428, 132514

4. Light-controlled fluorescent probes for precisely monitoring brain amyloid-β aggregates in Alzheimer‘s disease. Chemical Engineering Journal, 2022, 446, 137385

5. Differentiating Aβ40 and Aβ42 in amyloid plaques with a small molecule fluorescence probe. Chemical Science, 2020, 11: 5238-5245

6. Near-Infrared Light-Driven Nanoparticles for Cancer Photoimmunotherapy by Synergizing Immune Cell Death and Epigenetic Regulation. Small, 2023, 2309202

7. Phototheranostic Agents Based on Nonionic Heptamethine Cyanine for Realizing Synergistic Cancer Phototherapy. Adv. Healthcare Mater. 2023, 2202817

8. Homotypic targeting upconversion nano-reactor for cascade cancer starvation and deep-tissue phototherapy. Biomaterials, 2020, 235,119765

9. A dual-site fluorescent probe for direct and highly selective detection of cysteine and its application in living cells. Biosensors and Bioelectronics, 2017, 92, 583-588

10. Organic small molecule-based photothermal agents for cancer therapy: Design strategies from single-molecule optimization to synergistic enhancement. Coordination Chemistry Reviews, 2022, 464, 214564